References

Bota DP, Ferreira FL, Melot C, Vincent JL Body temperature alterations in the critically ill. Intensive Care Med. 2004; 30:(5)811-6 https://doi.org/10.1007/s00134-004-2166-z

Corfield AR, Lees F, Zealley I Utility of a single early warning score in patients with sepsis in the emergency department. Emerg Med J. 2013; 31:(6)482-7 https://doi.org/10.1136/emermed-2012-202186

Cronshaw HL, Daniels R, Bleetman A, Joynes E, Sheils M Impact of the Surviving Sepsis Campaign on the recognition and management of severe sepsis in the emergency department: are we failing?. Emerg Med J. 2011; 28:(8)670-5 https://doi.org/10.1136/emj.2009.089581

Daniels R Surviving the first hours in sepsis: getting the basics right: an intensivist's perspective. J Antimicrob Chemother. 2011; 66:11-23 https://doi.org/10.1093/jac/dkq515

Daniels R, 3rd edn. Sutton Coldfield: UK Sepsis Trust; 2014

Daniels R, Nutbeam T, McNamara G, Galvin C The sepsis six and the severe sepsis resuscitation bundle: a prospective observational cohort study. Emerg Med J. 2011; 28:(6)507-12 https://doi.org/10.1136/emj.2010.095067

Dellinger RP, Levy MM, Rhodes A Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012. Crit Care Med. 2013; 41:(2)580-637 https://doi.org/10.1097/CCM.0b013e31827e83af

Erwin A, Salzman J, Wewerka S, Burnett A, Frascone RJ Can paramedics accurately diagnose sepsis and severe sepsis in the field? (abstract). Acad Emerg Med. 2011; 18:(5)S23-4 https://doi.org/10.1111/j.1553-2712.2011.01073.x

Gerber K Surviving sepsis: a trust-wide approach. A multi-disciplinary team approach to implementing evidence-based guidelines. Nurs Crit Care. 2010; 15:(3)141-51 https://doi.org/10.1111/j.1478-5153.2009.00378.x

Guerra WF, Mayfield TR, Meyers MS, Clouatre AE, Riccio JC Early detection and treatment of patients with severe sepsis by prehospital personnel. J Emerg Med. 2013; 44:(6)1116-25 https://doi.org/10.1016/j.jemermed.2012.11.003

Gray A, Ward K, Lees F The epidemiology of adults with severe sepsis and septic shock in Scottish emergency departments. Emerg Med J. 2013; 30:(5)397-401 https://doi.org/10.1136/emermed-2012-201361

Herlitz J, Bang A, Wireklint-Sundström B Suspicion and treatment of severe sepsis. An overview of the prehospital chain of care. Scand J Trauma Resusc Emerg Med. 2012; 20 https://doi.org/10.1186/1757-7241-20-42

Keep JW, Messmer AS, Sladden R National early warning score at Emergency Department triage may allow earlier identification of patients with severe sepsis and septic shock: a retrospective observational study. Emerg Med J. 2015; https://doi.org/10.1136/emermed-2014-204465

Mann CJ Observational research methods. Research design II: cohort, cross sectional, and case-control studies. Emerg Med J. 2003; 20:(1)54-60 https://doi.org/10.1136/emj.20.1.54

Marik PE Surviving sepsis: going beyond the guidelines. Ann Intensive Care. 2011; 1:(1) https://doi.org/10.1186/2110-5820-1-17

McClelland G, Younger P A Study into pre-alerts to North East hospitals for sepsis. Journal of Paramedic Practice. 2013; 5:(7)408-15 https://doi.org/10.12968/jpar.2013.5.7.408

Moran D Infections in the elderly. Top Emerg Med. 2003; 25:(2)174-81

Nguyen SQ, Mwakalindile E, Booth JS Automated electronic medical record sepsis detection in the emergency department. PeerJ. 2014; 2 https://doi.org/10.7717/peerj.343

Parliamentary and Health Service Ombudsman. 2013. http//www.ombudsman.org.uk/__data/assets/pdf_file/0004/22666/FINAL_Sepsis_Report_web.pdf (accessed 26 August 2015)

Robson W, Daniels R Diagnosis and management of sepsis in adults. Nurse Prescribing. 2013; 11:(2)76-82 https://doi.org/10.12968/npre.2013.11.2.76

London: RCP; 2012

Seymour CW, Cooke CR, Mikkelsen ME Out-of-hospital fluid in severe sepsis: effect on early resuscitation in the emergency department. Prehosp Emerg Care. 2010; 14:(2)145-52 https://doi.org/10.3109/10903120903524997

Seymour CW, Rea TD, Kahn JM, Walkey AJ, Yealy DM, Angus DC Severe sepsis in pre-hospital emergency care: analysis of incidence, care, and outcome. Am J Respir Crit Care Med. 2012; 186:(12)1264-71 https://doi.org/10.1164/rccm.201204-0713OC

Travers A, Green R, Cain E, Campbell SG, Jensen JL, Petrie D Can paramedics diagnose sepsis in the prehospital setting? A feasibility study (abstract). CJEM. 2013; 15

Wallgren UM, Castrén M, Svensson AE, Kurland L Identification of adult septic patients in the prehospital setting: a comparison of two screening tools and clinical judgement. Eur J Emerg Med. 2014; 21:(4)260-5 https://doi.org/10.1097/MEJ.0000000000000084

Younger P, McClelland G Evaluation of pre-hospital point of care testing for lactate in sepsis and trauma patients. Journal of Paramedic Practice. 2014; 6:(10)526-31 https://doi.org/10.12968/jpar.2014.6.10.526

Zeni F, Freeman B, Natanson C Anti-inflammatory therapies to treat sepsis and septic shock: a reassessment. Crit Care Med. 1997; 25:(7)1095-100 https://doi.org/10.1097/00003246-199707000-00001

A pilot study exploring the accuracy of pre-hospital sepsis recognition in the North East Ambulance Service

02 September 2015
Volume 7 · Issue 9

Abstract

Background:

Over the past decade there has been a focus on improving pre-hospital recognition and treatment of patients with sepsis. This pilot study investigates pre-hospital sepsis recognition, including the use of a Sepsis Screening Tool (SST), treatment and whether timely identification influenced the time to treatment and outcome at the receiving unit.

Methods:

A cross-sectional sample of patients with a documented suspicion of sepsis by North East Ambulance Service NHS Foundation Trust (NEAS) was combined and cross referenced with patients coded for sepsis at The James Cook University Hospital (JCUH) to generate a sample of sepsis patients seen within January 2014. NEAS sepsis recognition was compared with SST identification by retrospectively examining patients' medical records. Sensitivity and specificity for NEAS diagnosis were calculated by comparing NEAS identification with JCUH diagnosis using the hospital SST.

Results:

The sample included 49 patients from January 2014. NEAS correctly identified 18/42 patients with sepsis (43% sensitivity, 14% specificity). NEAS correctly identified 8/27 patients with severe sepsis (30% sensitivity, 77% specificity).

Conclusions:

It is evident that NEAS clinicians diagnose sepsis without consistently using the SST. Use of the SST would improve the ability of NEAS clinicians to identify patients with sepsis.

This pilot study will explore sepsis recognition by North East Ambulance Service NHS Foundation Trust (NEAS), estimate the sensitivity and specificity of paramedic identification of sepsis and examine use of the Sepsis Screening Tool (SST) (See Appendix 1).

NEAS trained all clinical staff in sepsis recognition using the SST between April 2012 and March 2013 in order to improve awareness, detection and treatment of this previously ill-defined condition. Sepsis was covered in a 1-hour session, during the two-day essential annual training. The SST is based on the tool developed by the UK Sepsis Trust (UKST) and adapted locally by the North East Critical Care Network (NECCN) but has not been validated in a pre-hospital setting. The SST was updated in June 2014, in line with recommendations from the NECCN, to include oxygen saturations as a trigger of organ dysfunction. The updated version is referred to as SST+.

Subscribe to get full access to the Journal of Paramedic Practice

Thank you for visiting the Journal of Paramedic Practice and reading our archive of expert clinical content. If you would like to read more from the only journal dedicated to those working in emergency care, you can start your subscription today for just £48.

What's included

  • CPD Focus

  • Develop your career

  • Stay informed