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Evaluation of pre-hospital point-of-care testing for lactate in sepsis and trauma patients

02 October 2014
Volume 6 · Issue 10

Abstract

Objective: Lactate is a significant marker of critical illness and mortality in sepsis and trauma patients. The purpose of this study is to evaluate point-of-care lactate testing by paramedics in a UK ambulance service.

Methods: Selected enhanced care paramedics were trained to use the lactate meter in patients with suspected sepsis and patients who trigger the major trauma bypass protocol. Feedback was collected on the practicalities of using the meter and the potential impact on the diagnosis of sepsis.

Results: Data were collected on 114 patients, 96% had suspected sepsis (n=109) and 4% (n=5) were patients who had sustained trauma. The participants found that the ability to take lactate readings was useful and increased their confidence in their clinical decision making.

Conclusions: Point-of-care lactate measurement is feasible in pre-hospital care and appears to support paramedics in their decision making.

North East Ambulance Service NHS Foundation Trust (NEAS) covers the north east of England and employs around 1 000 accident and emergency staff across 57 locations who serve a population of 2.6 million people.

As part of the NEAS drive to improve patient care, a sepsis screening tool (SST) was introduced into practice in April 2012 (Figure 1) based on the recommendations of the Surviving Sepsis Campaign (Dellinger et al, 2008). These recommendations were later superseded in the ‘Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2012’ (Dellinger et al, 2012).

One of the criteria for severe sepsis on the SST is a lactate of >2 mmol/L, which NEAS paramedics have previously been unable to measure. The potential use of lactate in pre-hospital care has been reported elsewhere by the authors (McClelland et al, 2012) and provided some of the background for this study.

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