References

Greene S, Kerins M, O'Connor N Pre-hospital activated charcoal: the way forward. Emerg Med J. 2005; 22:(10)734-7 https://doi.org/10.1136/emj.2005.024968

Longworth L, Young T, Buxton M Midterm cost-effectiveness of the liver transplantation programme of England and Wales for three disease groups. Liver Transpl. 2003; 9:(12)1295-307 https://doi.org/10.1016/j.lts.2003.09.012

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National Poisons Information Service. 2013. http//www.toxbase.org/Utils/login.aspx?ReturnUrl=%2fChemicals%2fManagement-Pages%2fParacetamol-Index-UK%2f (accessed 14 September 2015)

Office for National Statistics. The National Diet and Nutrition Survey: adults aged 19 to 64 years. 2001. http//www.ons.gov.uk/ons/rel/lifestyles/the-national-diet-and-nutrition-survey/index.html (accessed 10 August 2015)

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Walker R Single-dose activated charcoal as a pre-hospital treatment for self-poisoning. Journal of Paramedic Practice. 2013; 5:(8)448-53 https://doi.org/10.12968/jpar.2013.5.8.448

Single–dose activated charcoal—a feasibility study in an ambulance setting

02 October 2015
Volume 7 · Issue 10

Abstract

Following a previous article published in the Journal of Paramedic Practice (Walker, 2013) this article summarises the findings of a study conducted by South Western Ambulance Service NHS Foundation Trust (SWASFT). As a result of the literature review detailed in the previous article, approval was given to run a 6-month study examining the feasibility of paramedic crews carrying and administering single-dose activated charcoal (SDAC) to patients of self-poisoning attended within 1 hour of ingestion of a suitable toxin. Sixty nine patients were offered SDAC, with an acceptance rate of 94%. Fears of adverse incidents such as vomiting, aspiration and increased time on scene appeared almost entirely unfounded and crews found the medication easy to use and popular with patients. Paracetamol, usually at hepatotoxic levels accounted for 57% of all overdoses encountered, most of these receiving SDAC within 1 hour, with 81.5% of all patients receiving the medication in that time frame. SWASFT has now adopted SDAC as a treatment for patients of overdose.

In 2004, a clinical guideline from the National Institute for Health and Care Excellence (NICE) recommended that the evidence supported administration of single-dose activated charcoal (SDAC) within 1 hour of toxin ingestion and that ambulance services were ideally placed to deliver this treatment (NICE, 2004).

A survey the following year (Greene et al, 2005) found that no ambulance services had adopted the treatment, citing concerns which included the lack of a protocol aimed at ambulance staff, increased time on scene, and vomiting by patients with associated ambulance cleaning and increased turnaround times.

A literature review conducted by South Western Ambulance Service NHS Foundation Trust (SWASFT) in 2012—detailed in a previous article (Walker, 2013)—concluded that sufficient evidence of clinical benefit existed to warrant a trial of SDAC as a treatment within SWASFT.

The primary aim of the trial was to evaluate the feasibility of crews carrying and administering the medication to suitable patients in a pre-hospital setting, in particular examining the concerns raised by ambulance Trusts in the paper by Greene et al (2005). The secondary aim was to describe the patient demographic of those receiving or refusing the treatment offered.

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