A single-centre, prospective cohort study was conducted by North East Ambulance Service NHS Foundation Trust between 17 February 2020 and 31 March 2021..
North West–Greater Manchester North West Research Ethics Committee (18/NW/0763) and the Health Research Authority provided ethics approval for this study..
Lactate is produced by most tissues in the human body, with the highest level of lactate production found in muscle (Consoli et al, 1990). In healthy subjects, lactate is the result of pyruvate...
Sepsis is a life-threatening condition with estimates of up to 37 000 deaths annually in the UK alone. When sepsis is not treated the mortality rate increases by 8% every hour (Cronshaw et al, 2011)....