References

Bernard S, Gray T, Buist M Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002; 346:(8)557-63

Binks A, Murphy R, Prout R Therapeutic hypothermia after cardiac arrest— implementation in UK intensive care units. Anaesthesia. 2010; 65:(3)260-5

Busch M, Soreide E, Lossius H Rapid implementation of therapeutic hypothermia in comatose out of hospital cardiac arrest survivors. Acta Anaesthesiol Scand. 2006; 50:(10)1277-83

Jennett B, Bond M Assessment of outcome after severe brain damage. Lancet. 1975; 1:(7905)480-4

Mooney M, Barbara T, Unger RN Therapeutic hypothermia after out-of-hospital cardiac arrest: evaluation of a regional system to increase access to cooling. Circulation. 2011; 124:206-214

Nolan J, Morley P, Vanden Hoek T Therapeutic hypothermia after cardiac arrest: an advisory statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation. Circulation. 2003; 108:(1)118-21

Nolan J, Deakin C, Soar J European Resuscitation Council Guidelines for Resuscitation: Section 4. Adult advanced life support. Resuscitation. 2005; 67S:(1)S39-S86

Nolan J, Soar J, Zideman D European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary. Resuscitation. 2010; 81:1219-76

mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med. 2002; 346:(8)549-56

Discussing therapeutic hypothermia and the ‘Cool it’ study

07 October 2011
Volume 3 · Issue 10

‘Therapeutic hypothermia (TH) improves survival and confers neuroprotection in out of hospital cardiac arrest (OHCA).’

This is a statement that is rapidly becoming a universally accepted position in acute and emergency healthcare worldwide. Surprisingly, there continues to be a slow uptake of the technologies on offer, despite the apparent patient benefit.

Following the publication of two seminal TH articles in 2002 (Bernard et al; The Hypothermia After Cardiac Arrest Study Group, 2002), and the subsequent International Liaison Committee on Resuscitation recommendations in 2003 (Nolan et al, 2003), there has been a steady implementation of the therapy into intensive care units throughout the UK. This, however, has taken somewhat longer than what should have been reasonably expected.

A study performed by Bink et al (2010) conducted a telephone survey of all 247 intensive care departments within the NHS and found that the vast majority (85.6%) of departments are now using some form of TH in their standard care package following sudden cardiac arrest.

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