The primary aim of this work was to review the UK-based literature to understand: whether the administration of IV antibiotics by the ambulance service to septic patients is associated with improved...
A systematic search was conducted to find strong primary quantitative research to determine to what extent low EtCO2 is a predictor of sepsis and if this has diagnostic value..
The objectives of this review are to: explore the potential value of intravenous ascorbic acid as a primary treatment for sepsis in the prehospital environment; and find out whether it can reduce...
All PCRs from patients assessed by DFB prehospital practitioners in the week starting 27 March 2017 were manually examined by an independent researcher to identify patients with potential sepsis or...
The aim of this study was to illuminate the views of medical directors in NHS ambulance services, associated with the use of IV antibiotics to treat prehospital sepsis..
A small ambulance station within South Western Ambulance Service NHS Foundation Trust (SWAST) was purposively selected to participate in the study based on its size, location, usual patient numbers...
Systematic searches identified 1 461 study abstracts which were evaluated against the inclusion/exclusion criteria for relevance. A total of 65 studies were potentially relevant and full texts were...
‘an overwhelming uncontrolled, systemic inflammatory response which is mediated by the immune system, the vascular endothelium and inflammatory pathways in response to an infective trigger’ .
‘Similar to an acute myocardial ischaemic attack and an acute brain attack, the speed and appropriateness of therapy administered in the initial hours after the syndrome develops are likely to...
The Pre-hospital Piperacillin/Tazobactam (PrePip) project tested the concept that UK paramedics could accurately recognise sepsis, aseptically take blood cultures, and safely and rapidly treat septic...
It is estimated there are at least 100 000 cases of severe sepsis each year in the UK, although the true prevalence of sepsis may be higher due to under recognition (Cronshaw et al, 2011). Mortality...
A comprehensive literature review was completed to evaluate the available evidence, undertaken in late 2013.
This study was designed to examine the feasibility, and potential impacts, of introducing POC lactate measurement into pre-hospital care within NEAS. The primary objective was to evaluate the Nova...
Sepsis is a life-threatening condition with estimates of up to 37 000 deaths annually in the UK alone. When sepsis is not treated the mortality rate increases by 8% every hour (Cronshaw et al, 2011)....
In patients presenting with sepsis, severe sepsis and septic shock, could lactate testing assist with pre-hospital identification?.
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