Sepsis

To what extent is end-tidal carbon dioxide a predictor of sepsis?

A systematic search was conducted to find strong primary quantitative research to determine to what extent low EtCO2 is a predictor of sepsis and if this has diagnostic value..

Should ascorbic acid be a primary therapy for sepsis in prehospital settings?

The objectives of this review are to: explore the potential value of intravenous ascorbic acid as a primary treatment for sepsis in the prehospital environment; and find out whether it can reduce...

Prehospital sepsis care in Ireland: an audit

All PCRs from patients assessed by DFB prehospital practitioners in the week starting 27 March 2017 were manually examined by an independent researcher to identify patients with potential sepsis or...

Treating sepsis in the emergency prehospital setting with IV antibiotics

The aim of this study was to illuminate the views of medical directors in NHS ambulance services, associated with the use of IV antibiotics to treat prehospital sepsis..

Pre-hospital lactate testing in the recognition and management of sepsis and septic shock

A small ambulance station within South Western Ambulance Service NHS Foundation Trust (SWAST) was purposively selected to participate in the study based on its size, location, usual patient numbers...

Can handheld POC capillary lactate measurement be used with arterial and venous laboratory testing methods in the identification of sepsis?

Systematic searches identified 1 461 study abstracts which were evaluated against the inclusion/exclusion criteria for relevance. A total of 65 studies were potentially relevant and full texts were...

A clinical review of the indications for, and subsequent implementation of, a pilot pre-hospital sepsis pathway within NWAS

‘an overwhelming uncontrolled, systemic inflammatory response which is mediated by the immune system, the vascular endothelium and inflammatory pathways in response to an infective trigger’ .

Moving sepsis care to the front line: knowledge and views of pre-hospital clinicians

‘Similar to an acute myocardial ischaemic attack and an acute brain attack, the speed and appropriateness of therapy administered in the initial hours after the syndrome develops are likely to...

Can paramedics treat sepsis?

The Pre-hospital Piperacillin/Tazobactam (PrePip) project tested the concept that UK paramedics could accurately recognise sepsis, aseptically take blood cultures, and safely and rapidly treat septic...

A pilot study exploring the accuracy of pre-hospital sepsis recognition in the North East Ambulance Service

It is estimated there are at least 100 000 cases of severe sepsis each year in the UK, although the true prevalence of sepsis may be higher due to under recognition (Cronshaw et al, 2011). Mortality...

Can pre-hospital recognition and intervention improve outcome for patients with severe sepsis?

A comprehensive literature review was completed to evaluate the available evidence, undertaken in late 2013.

Evaluation of pre-hospital point-of-care testing for lactate in sepsis and trauma patients

This study was designed to examine the feasibility, and potential impacts, of introducing POC lactate measurement into pre-hospital care within NEAS. The primary objective was to evaluate the Nova...

Pre-hospital lactate monitoring for adults with sepsis

Sepsis is a life-threatening condition with estimates of up to 37 000 deaths annually in the UK alone. When sepsis is not treated the mortality rate increases by 8% every hour (Cronshaw et al, 2011)....

Pre-hospital lactate testing in the identification of patients with sepsis: a review of the literature

In patients presenting with sepsis, severe sepsis and septic shock, could lactate testing assist with pre-hospital identification?.

A study into pre-alerts to North East hospitals for sepsis

The authors explored a number of options for collecting data on the incidence of pre-hospital sepsis within their area. In the Electronic Patient Report Form (EPRF) used in NEAS there is no category...

Why choose the Journal of Paramedic Practice?

The Journal of Paramedic Practice supports paramedics by sharing expertise and advice to help you build confidence, grow professionally and improve care.

What's included

  • Evidence-based best practice

  • Peer-reviewed research

  • Practical guidance

  • CPD support

Subscriptions start:

From £14.75 GBP