Shock

Prehospital administration of calcium in trauma

Calcium ions initiate actin-myosin filament binding, resulting in myofibril (muscle-fibre) shortening and muscle contraction. Depletion of calcium ions because of loss during haemorrhage and...

Pre-hospital management of major haemorrhage following trauma: part one

Bleeding within the body affects two principal physiological systems:.

Recognising and managing severe sepsis in the pre-hospital environment

Sepsis is a common condition in which the body over reacts to a severe infection. During a period of infection a normal inflammatory response is essential, as the body increases the permeability of...

Lactate measurement in pre-hospital care: a review of the literature

Lactate was frst described in the late 18th century by KW Scheele, a Swedish chemist. Lactate can be produced in all bodily tissue but is mainly produced by the skeletal muscles, skin, red blood...

Adult sepsis in a pre-hospital environment

Sepsis occurs when a simple infection develops to cause an overwhelming, inappropriate infammatory response. The causative pathogen is identifed by the host's innate (non-specifc) immune system, which...

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