Toxicity

Use of flumazenil to treat poisoning in prehospital care

Chacko and Peter (2019) define antidotes as agents that reverse the effects of poisons on the body. Their mode of action is achieved by enzyme inhibition, binding to and neutralising a poison,...

Gamma-hydroxybutyrate (GHB): a review for the prehospital clinician

The literature search identified 387 results and, once duplicates had been removed, 262 results remained. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method (Moher...

Does digoxin cause more harm than good?

Digoxin has a very narrow therapeutic margin between toxicity and efficacy, which results in a high incidence of digoxin toxicity (Larsen, 2009). To avoid toxicity, digoxin dosage must be adjusted...

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