References

Ali A, Zachrison KS, Eschenfeldt PC, Schwamm LH, Hur C. Optimization of Prehospital Triage of Patients With Suspected Ischemic Stroke: Results of a Mathematical Model. Stroke. 2018; 49:(10)2532-2535 https://doi.org/10.1161/STROKEAHA.118.022041

Berkhemer OA, Fransen PS, Beumer D A randomized trial of intraarterial treatment for acute ischemic stroke. New Engl J Med. 2015; 372:(1)11-20 https://doi.org/10.1056/NEJMoa1411587

Cameron P, Jelinek G, Kelly A, Brown A, Little M Textbook of adult emergency medicine.(eds). Edinburgh: Churchill Livingstone/Elsevier; 2015

Chen Z, Zhang R, Xu F Novel prehospital prediction model of large vessel occlusion using artificial neural network. Front Aging Neurosci. 2018; 10 https://doi.org/10.3389/fnagi.2018.00181.eCollection2018

Davis SM, Campbell BC, Donnan GA. Endovascular thrombectomy and stroke physicians: equity, access, and standards. Stroke. 2017; 48:2042-2044 https://doi.org/10.1161/STROKEAHA.117.018208

Demeestere J, Garcia-Esperon C, Lin L Validation of the National Institutes of Health stroke scale-8 to detect large vessel occlusion in ischemic stroke. J Stroke Cerebrovasc Dis. 2017a; 26:(7)1419-1426

Demeestere J, Garcia-Esperon C, Lin L, Loudfoot A, Bivard A, Parsons M Abstract WP276: Simplification of a Prehospital Short NIHSS Scale Does not Increase Interrater Agreement Between Emergency Medical Services and Stroke Specialists. Stroke. 2017b; 48:AWP276-AWP

Fothergill RT, Williams J, Edwards MJ, Russell IT, Gompertz P. Does use of the recognition of stroke in the emergency room stroke assessment tool enhance stroke recognition by ambulance clinicians?. Stroke. 2013; 44:(11)3007-3012

Gao J, Dai Q, Liu X. Endovascular treatment for acute ischemic stroke: updates and future implications. Interventional Neurol. 2015; 4:(1–2)43-47

Garbutt G, Davies P. Should the practice of medicine be a deontological or utilitarian enterprise?. J Med Ethics. 2011; 37:(5)267-270

Hastrup S, Damgaard D, Johnsen SP, Andersen G. Prehospital acute stroke severity scale to predict large artery occlusion: design and comparison with other scales. Stroke. 2016; 47:(7)1772-1776

Hui FK, El Mekabaty A, Schultz J Helistroke: neurointerventionalist helicopter transport for interventional stroke treatment: proof of concept and rationale. J NeuroInterventional Surg. 2018; 10:(3)225-228

King's College London. Sentinel Stroke National Audit Programme. Clinical audit national annual results portfolio: April 2017–Mar 2018. 2018. https//tinyurl.com/y565ecdq (accessed 26 March 2019)

Krebs W, Sharkey-Toppen TP, Cheek F Prehospital stroke assessment for large vessel occlusions: a systematic review. Prehospital emergency care. Prehosp Emerg Care. 2018; 22:(2)180-188 https://doi.org/10.1080/10903127.2017.1371263

Leira EC, Savitz SI. In the Era of Thrombectomy, Let Us Also Protect the Majority of Patients With Stroke Who Only Require Medical Treatment!. Stroke. 2018; 49:(6)1538-1540

Leslie-Mazwi T, Chandra RV, Fraser JF AHA/ASA 2018 AIS guidelines: impact and opportunity for endovascular stroke care. J Neurointerventional Surg. 2018;

McHugh ML. Interrater reliability: the kappa statistic. Biochemia Medica. 2012; 22:(3)276-282

Mocco J, Fiorella D, Albuquerque FC. The mission lifeline severity-based stroke treatment algorithm: We need more time. J NeuroInterventional Surg. 2017; 9:(5)427-428

Nazliel B, Starkman S, Liebeskind DS A brief prehospital stroke severity scale identifies ischemic stroke patients harboring persisting large arterial occlusions. Stroke. 2008; 39:(8)2264-2267

Noorian A, Sanossian N, Liebeskind DS Field validation of prehospital lams score to identify large vessel occlusion ischemic stroke patients for direct routing to emergency neuroendovascular centers. Stroke. 2016; 47:A83LP-A83

Noorian AR, Sanossian N, Shkirkova K Los Angeles Motor Scale to identify large vessel occlusion: prehospital validation and comparison with other screens. Stroke. 2018; 49:(3)565-572

Current, future and avoidable costs of stroke in the UK. Executive summary Part 2: Societal costs of stroke in the next 20 years and potential returns from increased spending on research. 2017. https//tinyurl.com/y9ev7q75 (accessed 20 April 2018)

Pérez de la Ossa N, Carrera D, Gorchs M, Querol M, Millán M, Gomis M Design and validation of a prehospital stroke scale to predict large arterial occlusion: the rapid arterial occlusion evaluation scale. Stroke. 2014; 45:(1)87-91

Pérez de la Ossa N, Ribó M, Jiménez X, Abilleira S. Prehospital scales to identify patients with large vessel occlusion: It is time for action. Stroke. 2016; 47:(11)2877-2878

Powers WJ, Rabinstein AA, Ackerson T Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2018; 49:e46-e110

Toyoda K. Epidemiology and Registry Studies of Stroke in Japan. J Stroke. 2013; 15:(1)21-26

Uchida K, Yoshimura S, Hiyama N Clinical prediction rules to classify types of stroke at prehospital stage: Japan Urgent Stroke Triage (JUST) Score. Stroke. 2018; 49:(8)1820-1827 https://doi.org/10.1161/STROKEAHA.118.021794

Vivanco-Hidalgo RM, Abilleira S, Salvat-Plana M, Ribera A, Gallofré G, Gallofre M. Innovation in Systems of Care in Acute Phase of Ischemic Stroke. The Experience of the Catalan Stroke Programme. Front Neurol. 2018; 9

Wei D, Oxley TJ, Nistal DA Mobile interventional stroke teams lead to faster treatment times for thrombectomy in large vessel occlusion. Stroke. 2017; 48:(12)3295-3300

Whelley-Wilson CM, Newman GC. A stroke scale for emergency triage. J Stroke Cerebrovasc Dis. 2004; 13:(6)247-253

Zaidi SF, Shawver J, Morales AE Stroke care: initial data from a county-based bypass protocol for patients with acute stroke. J Neurointerventional Surg. 2016;

Zhao H, Coote S, Pesavento L Large vessel occlusion scales increase delivery to endovascular centers without excessive harm from misclassifications. Stroke. 2017; 48:(3)568-573

Zhao H, Pesavento L, Coote S Ambulance clinical triage for acute stroke treatment: paramedic triage algorithm for large vessel occlusion. Stroke. 2018; 49:(4)945-951

Advanced prehospital stroke triage in the era of mechanical thrombectomy

02 April 2019
Volume 11 · Issue 4

Abstract

Direct transport to a comprehensive stroke centre that is capable of endovascular thrombectomy may improve outcomes in patients with large vessel occlusive stroke. A number of prehospital triage tools have been developed to see if clinicians can predict which patients would benefit from this procedure, allowing them to bypass a primary stroke centre in preference for a comprehensive stroke centre. A literature search was performed across a number of medical databases; six triage tools were selected for analysis based on their reported accuracy and prevalence in clinical trials. Additionally, a number of articles were isolated for the analysis of changing systems of care for patients who had had a stroke. This narrative review integrates how these variously accurate triage tools could benefit patients and outlines why changes to the system of care for stroke patients require a ground-upwards, local approach. The accuracy of the triage tools analysed varied, with some lacking specificity and others sensitivity. Triage tools are evolving, and simplistic tools offer comparable accuracy when contrasted with comprehensive alternatives, which require a significantly increased level of assessment skill and time demand. While there is evidence in support of prehospital bypass protocols, this evidence is poorly generalisable owing to a number of variables, with geographical layout being a significant compounding factor.

Stroke is a neurological emergency that results from the disruption of blood supply to part of the brain, either by infarction or haemorrhage. In the UK alone, there are more than 100 000 strokes each year; its mortality is signified by its place as the fourth biggest killer nationally (King's College London, 2018). Despite many advances in management, acute ischaemic stroke remains a leading cause of death and disability in the UK. With the cost to society estimated at £26 billion per year, medical research has focused on improving the initial recognition and treatment of these patients (Patel et al, 2017). In the mid 1990s, the importance of prehospital stroke identification accelerated with the introduction of intravenous tissue-type plasminogen activator (tPA) as a successful management strategy for ischaemic stroke (Cameron et al, 2015). These drugs are effective only if administered rapidly after the onset of stroke symptoms (Cameron et al, 2015).

Subscribe to get full access to the Journal of Paramedic Practice

Thank you for visiting the Journal of Paramedic Practice and reading our archive of expert clinical content. If you would like to read more from the only journal dedicated to those working in emergency care, you can start your subscription today for just £48.

What's included

  • CPD Focus

  • Develop your career

  • Stay informed