References

Academy of Medical Sciences. COVID-19: Preparing for the future. Looking ahead to winter 2021/22 and beyond. 2021. https//acmedsci.ac.uk/file-download/4747802 (accessed 29 November 2021)

Adlhoch C, Mook P, Lamb F Very little influenza in the WHO European Region during the 2020/21 season, weeks 40 2020 to 8 2021. Euro Surveill. 2021; 26:(11) https://doi.org/10.2807/1560-7917.ES.2021.26.11.2100221

Alene M, Yismaw L, Assemie MA Magnitude of asymptomatic COVID-19 cases throughout the course of infection: A systematic review and meta-analysis. PloS One. 2021; 16:(3) https://doi.org/10.1371/journal.pone.0249090

Aujard Y, Fauroux B. Risk factors for severe respiratory syncytial virus infection in infants. Respir Med. 2002; 96:S9-S14 https://doi.org/10.1053/rmed.2002.1295

Azer SA. COVID-19: pathophysiology, diagnosis, complications and investigational therapeutics. New Microbes New Infect. 2020; 37 https://doi.org/10.1016/j.nmni.2020.100738

Barr R, Green CA, Sande CJ, Drysdale SB. Respiratory syncytial virus: diagnosis, prevention and management. Ther Adv Infect Dis. 2019; 6 https://doi.org/10.1177/2049936119865798

Bernardo CO, Gonzalez-Chica D, Stocks N. Influenza-like illness and antimicrobial prescribing in Australian general practice from 2015 to 2017: a national longitudinal study using the MedicineInsight dataset. BMJ Open. 2019; 9:(4) https://doi.org/10.1136/bmjopen-2018-026396

Butler CC, van der Velden AW, Bongard E Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial. Lancet. 2020; 395:(10217)42-52 https://doi.org/10.1016/S0140-6736(19)32982-4

Centers of Disease Control and Prevention. Human parainfluenza viruses (HPIVs). 2019. https//www.cdc.gov/parainfluenza/hcp/clinical.html (accessed 28 November 2021)

Centers for Disease Control and Prevention. Handwashing: clean hands save lives. 2021. https//www.cdc.gov/handwashing/index.html (accessed 28 November 2021)

Collins PL, Fearns R, Graham BS. Respiratory syncytial virus: virology, reverse genetics, and pathogenesis of disease. Curr Top Microbiol Immunol. 2013; 372:3-38 https://doi.org/10.1007/978-3-642-38919-1_1

Cucinotta D, Vanelli M. WHO declares COVID-19 a pandemic. Acta Biomed. 2020; 91:(1)157-160 https://doi.org/10.23750/abm.v91i1.9397

Dela Cruz CS, Pasnick S, Gross JE Adenovirus infection and outbreaks: what you need to know. Am J Respir Crit Care Med. 2019; 199:(7)P13-P14 https://doi.org/10.1164/rccm.1997P13

Department of Health and Social Care. Research and analysis: evidence summary for lateral flow devices (LFD) in relation to care homes. 2020. https//tinyurl.com/22e88xju (accessed 28 November 2021)

Dhochak N, Singhal T, Kabra SK, Lodha R. Pathophysiology of COVID-19: why children fare better than adults?. Indian J Pediatr. 2020; 87:(7)537-546 https://doi.org/10.1007/s12098-020-03322-y

Dolk FCK, Pouwels KB, Smith DRM, Robotham JV, Smieszek T. Antibiotics in primary care in England: which antibiotics are prescribed and for which conditions?. J Antimicrob Chemother. 2018; 73:ii2-ii10 https://doi.org/10.1093/jac/dkx504

Du R, Cui Q, Rong L. Flu Universal vaccines: new tricks on an old virus. Virol Sin. 2021; 36:(1)13-24 https://doi.org/10.1007/s12250-020-00283-6

Fitzner J, Qasmieh S, Mounts AW Revision of clinical case definitions: influenza-like illness and severe acute respiratory infection. Bull World Health Organ. 2018; 96:(2)122-128 https://doi.org/10.2471/BLT.17.194514

Gibson PG, Qin L, Puah SH. COVID-19 acute respiratory distress syndrome (ARDS): clinical features and differences from typical pre-COVID-19 ARDS. Med J Aust. 2020; 213:(2)54-56.e1 https://doi.org/10.5694/mja2.50674

Grayson ML, Melvani S, Druce J Efficacy of soap and water and alcohol-based hand-rub preparations against live H1N1 influenza virus on the hands of human volunteers. Clin Infect Dis. 2009; 48:(3)285-291 https://doi.org/10.1086/595845

Green CA, Yeates D, Goldacre A Admission to hospital for bronchiolitis in England: trends over five decades, geographical variation and association with perinatal characteristics and subsequent asthma. Arch Dis Child. 2016; 101:(2)140-146 https://doi.org/10.1136/archdischild-2015-308723

Hall CB. Respiratory syncytial virus and parainfluenza virus. N Engl J Med. 2001; 344:(25)1917-1928 https://doi.org/10.1056/NEJM200106213442507

Ikonen N, Savolainen-Kopra C, Enstone JE Deposition of respiratory virus pathogens on frequently touched surfaces at airports. BMC Infect Dis. 2018; 18:(1) https://doi.org/10.1186/s12879-018-3150-5

Jefferson T, Jones MA, Doshi P Neuraminidase inhibitors for preventing and treating influenza in adults and children. Cochrane Database Syst Rev. 2014; 2014:(4) https://doi.org/10.1002/14651858.CD008965.pub4

Jutzeler CR, Bourguignon L, Weis CV Comorbidities, clinical signs and symptoms, laboratory findings, imaging features, treatment strategies, and outcomes in adult and pediatric patients with COVID-19: a systematic review and meta-analysis. Travel Med Infect Dis. 2020; 37 https://doi.org/10.1016/j.tmaid.2020.101825

Kalil AC, Thomas PG. Influenza virus-related critical illness: pathophysiology and epidemiology. Crit Care. 2019; 23:(1) https://doi.org/10.1186/s13054-019-2539-x

Karia R, Gupta I, Khandait H, Yadav A, Yadav A. COVID-19 and its modes of transmission. SN Compr Clin Med. 2020; 1-4 https://doi.org/10.1007/s42399-020-00498-4

Klein EY, Monteforte B, Gupta A The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis. Influenza Other Respir Viruses. 2016; 10:(5)394-403 https://doi.org/10.1111/irv.12398

Kong TK. Longer incubation period of coronavirus disease 2019 (COVID-19) in older adults. Aging Med (Milton). 2020; 3:(2)102-109 https://doi.org/10.1002/agm2.12114

Krammer F, Smith GJD, Fouchier RAM Influenza. Nat Rev Dis Primers. 2018; 4:(1) https://doi.org/10.1038/s41572-018-0002-y

Kutter JS, Spronken MI, Fraaij PL, Fouchier RA, Herfst S. Transmission routes of respiratory viruses among humans. Curr Opin Virol. 2018; 28:142-151 https://doi.org/10.1016/j.coviro.2018.01.001

Lauer SA, Grantz KH, Bi Q The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Intern Med. 2020; 172:(9)577-582 https://doi.org/10.7326/M20-0504

Lessler J, Reich NG, Brookmeyer R, Perl TM, Nelson KE, Cummings DA. Incubation periods of acute respiratory viral infections: a systematic review. Lancet Infect Dis. 2009; 9:(5)291-300 https://doi.org/10.1016/S1473-3099(09)70069-6

Little P, Stuart B, Moore M Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspected: a 12-country, randomised, placebo-controlled trial. Lancet Infect Dis. 2013; 13:(2)123-129 https://doi.org/10.1016/S1473-3099(12)70300-6

Low D. Reducing antibiotic use in influenza: challenges and rewards. Clin Microbiol Infect. 2008; 14:(4)298-306 https://doi.org/10.1111/j.1469-0691.2007.01910.x

Lynch JP, Kajon AE. Adenovirus: epidemiology, global spread of novel serotypes, and advances in treatment and prevention. Semin Respir Crit Care Med. 2016; 37:(4)586-602 https://doi.org/10.1055/s-0036-1584923

Michiels D. Reducing antibiotic use in influenza: challenges and rewards. Clin Microbiol Infect. 2008; 14:(4)298-306 https://doi.org/10.1111/j.1469-0691.2007.01910.x

Michiels B, Van Puyenbroeck K, Verhoeven V, Vermeire E, Coenen S. The value of neuraminidase inhibitors for the prevention and treatment of seasonal influenza: a systematic review of systematic reviews. PLoS One. 2013; 8:(4) https://doi.org/10.1371/journal.pone.0060348

National Institute for Health and Care Excellence. Amantadine, oseltamivir and zanamivir for the treatment of influenza. Technology appraisal guidance [TA168]. 2009. https//www.nice.org.uk/Guidance/TA168 (accessed 28 November 2021)

National Institute for Health and Care Excellence. Influenza—seasonal: scenario: treatment of influenza. 2020. https//cks.nice.org.uk/topics/influenza-seasonal/management/treating-influenza/ (accessed 28 November 2021)

National Institute for Health and Care Excellence. COVID-19 rapid guideline: managing COVID-19. NICE guideline [NG191]. 2021. https//www.nice.org.uk/guidance/ng191/ (accessed 28 November 2021)

Ortega H, Nickle D, Carter L. Rhinovirus and asthma: challenges and opportunities. Rev Med Virol. 2021; 31:(4) https://doi.org/10.1002/rmv.2193

Pormohammad A, Ghorbani S, Khatami A Comparison of influenza type A and B with COVID-19: s global systematic review and meta-analysis on clinical, laboratory and radiographic findings. Rev Med Virol. 2021; 31:(3) https://doi.org/10.1002/rmv.2179

Public Health England. Guidance: human parainfluenza viruses: clinical and public health management. 2008. https//tinyurl.com/2p8dbjae (accessed 28 November 2021)

Public Health England. Respiratory tract infections: infection control. 2016. https//tinyurl.com/2s3cx7p6 (accessed 28 November 2021)

Public Health England. Point of care tests for influenza and other respiratory viruses guidance. 2019. https//tinyurl.com/2p93u83e (accessed 28 November 2021)

Public Health England. Guidelines for PHE health protection teams on the management of outbreaks of influenza-like illness (ILI) in care homes. 2020a. https//tinyurl.com/yckp4nhj (accessed 28 November 2021)

Public Health England. Immunisation against infectious disease: the Green Book. 2020b. https//tinyurl.com/phymxa4j (accessed 28 November 2021)

Public Health England. Surveillance of influenza and other seasonal respiratory viruses in the UK: winter 2020 to 2021. 2021a. https//tinyurl.com/7hn24k73 (accessed 29 November 2021)

Public Health England. Investigation and management of outbreaks of suspected acute viral respiratory infection in schools: guidance for Health Protection Teams. 2021b. https//tinyurl.com/56v5emah (accessed 28 November 2021)

Public Health England. Respiratory syncytial virus (RSV): symptoms, transmission, prevention, treatment guidance. 2021c. https//tinyurl.com/a3jp8kj6 (accessed 28 November 2021)

Public Health England. COVID-19: guidance for maintaining services within health and care settings—infection prevention and control recommendations. 2021d. https//tinyurl.com/mrxyfcc4 (accessed 28 November 2021)

Richardson M, Elliman D, Maguire H, Simpson J, Nicoll A. Evidence base of incubation periods, periods of infectiousness and exclusion policies for the control of communicable diseases in schools and preschools. Pediatr Infect Dis J. 2001; 20:(4)380-391 https://doi.org/10.1097/00006454-200104000-00004

Russell E, Ison MG. Parainfluenza virus in the hospitalized adult. Clin Infect Dis. 2017; 65:(9)1570-1576 https://doi.org/10.1093/cid/cix528

Schomacker H, Schaap-Nutt A, Collins PL, Schmidt AC. Pathogenesis of acute respiratory illness caused by human parainfluenza viruses. Curr Opin Virol. 2012; 2:(3)294-299 https://doi.org/10.1016/j.coviro.2012.02.001

Sullivan JE, Farrar HC. Fever and antipyretic use in children. Pediatrics. 2011; 127:(3)580-587 https://doi.org/10.1542/peds.2010-3852

Solomon DA, Sherman AC, Kanjilal S. Influenza in the COVID-19 era. JAMA. 2020; 324:(13)1342-1343 https://doi.org/10.1001/jama.2020.14661

Struyf T, Deeks JJ, Dinnes J Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19. Cochrane Database Syst Rev. 2021; 2:(2) https://doi.org/10.1002/14651858.CD013665.pub2

To KKW, Yip CCY, Yuen KY. Rhinovirus—from bench to bedside. J Formos Med Assoc. 2017; 116:(7)496-504 https://doi.org/10.1016/j.jfma.2017.04.009

UK Health Security Agency. COVID-19: guidance for ambulance services. 2021. https//tinyurl.com/yckj5wwt (accessed 28 November 2021)

van Zyl-Smit RN, Richards G, Leone FT. Tobacco smoking and COVID-19 infection. Lancet Respir Med. 2020; 8:(7)664-665 https://doi.org/10.1016/S2213-2600(20)30239-3

Ward CF, Figiel GS, McDonald WM. Altered mental status as a novel initial clinical presentation for COVID-19 infection in the elderly. Am J Geriatr Psychiatry. 2020; 28:(8)808-811 https://doi.org/10.1016/j.jagp.2020.05.013

World Health Organization. Handwashing an effective tool to prevent COVID-19, other diseases. 2020. http//www.who.int/southeastasia/news/detail/15-10-2020-handwashing-an-effective-tool-to-prevent-covid-19-other-diseases (accessed 28 November 2021)

World Health Organization. Infection prevention and control. 2021. https//tinyurl.com/2p9f9fvu (accessed 28 November 2021)

Recognition and management of COVID-19 and other influenza-like illnesses: a guide for paramedics

02 December 2021
Volume 13 · Issue 12

Abstract

During the pandemic last year, the incidence of influenza-like illnesses (ILIs) was significantly lower, as preventive measures aimed to reduce the spread of COVID-19, were also successful in preventing the spread of other respiratory illnesses. With relaxed COVID-19 measures and the return of social contact and mixing, a significant increase in ILIs is anticipated this winter. Common causative pathogens for ILIs include influenza viruses, parainfluenza virus, respiratory syncytial virus (RSV), rhinovirus and SARS-CoV-2. With similar characteristics and mode of transmissions, it may be difficult to distinguish between these common respiratory pathogens. Fortunately, the majority of ILIs are self-limiting and treatments for these illnesses are similar: supportive treatment to relieve symptoms while awaiting recovery. Paramedics should be aware of the warning signs of serious diseases and consider admission if they occur. Finally, good infection prevention and control measures are vital to break the chain of transmission of ILIs and protect yourselves and others from them.

After reading this article, paramedics should be able to:

The world has been in pandemic mode for more than 18 months. The World Health Organization (WHO) declared SARS-CoV-2 as a global pandemic on 11 March 2020 (Cucinotta et al, 2020).

Interventions have been introduced to reduce the transmission of the virus, including handwashing, wearing masks and other personal protective equipment (PPE), social distancing, and school and workplace closures.

These interventions have been successful in preventing the transmission of COVID-19 and other diseases that have a similar mode of transmission. The European Centre for Disease Control reported a 99.4% reduction in influenza in winter 2020–2021 compared with the winter period in previous seasons (Adlhoch et al, 2021) and Public Health England (PHE, 2021a) reported similar findings, with primary care consultations, hospital and intensive care and high-dependency unit admissions related to influenza-like illnesses (ILIs) in winter 2020–2021 being below the baseline threshold levels from previous seasons.

Subscribe to get full access to the Journal of Paramedic Practice

Thank you for visiting the Journal of Paramedic Practice and reading our archive of expert clinical content. If you would like to read more from the only journal dedicated to those working in emergency care, you can start your subscription today for just £48.

What's included

  • CPD Focus

  • Develop your career

  • Stay informed