Abernethy AP, Currow DC, Frith P, Fazekas BS, McHugh A, Bui C Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. BMJ. 2003; 327:(7414)523-8
Abernethy AP, McDonald CF, Frith PA Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: a double-blind randomized controlled trial. Lancet. 2010; 376:(9743)784-93
Alldredge BK, Gelb AM, Isaacs SM A comparison of lorazepam, diazepam, and placebo for the treatment of out-ofhospital status epilepticus. N Engl J Med. 2001; 345:(9)631-7
Dyspnea. Mechanisms, assessment, and management: a consensus statement. American Thoracic Society. Am J Respir Crit Care Med. 1999; 159:(1)321-40
Bridgwater: Class Professional Publishing; 2013
Barnes H, McDonald J, Smallwood N, Manser R Opioids for the palliation of refractory breathlessness in adults with advanced disease and terminal illness. Cochrane Libr. 2014;
Bausewein C, Booth S, Gysels M, Higginson I Nonpharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases (review). Cochrane Database Syst Rev. 2008; (2)
Bausewein C, Farquhar M, Booth S, Gysels M, Higginson IJ Measurement of breathlessness in advanced disease: a systematic review. Respir Med. 2006; 101:(3)399-410
Bercovitch M., Waller A., Adunsky A. Multidimensional continuous pain assessment chart MCPAC for terminal cancer patients: a preliminary report. Am J Hosp Palliat Care. 2002; 19:(6)419-25
Booth S, Moffat C, Burkin J, Galbraith S, Bausewein C Nonpharmacological interventions for breathlessness. Curr Opin Support Palliat Care. 2011; 5:(2)77-86
Booth S, Moosavi SH, Higginson IJ The etiology and management of intractable breathlessness in patients with advanced cancer: a systematic review of pharmacological therapy. Nat Clin Pract Oncol. 2008; 5:(2)90-100
Boström B, Sandh M, Lundberg D, Fridlund B Cancer patients' experiences of care related to pain management before and after palliative care referral. Eur J cancer Care. 2004; 13:(3)238-45
Brady M Prehospital psychosocial care: changing attitudes. Journal of Paramedic Practice. 2012a; 4:(9)516-25
Brady M The concept of a ‘good death’ in pre-hospital care. Journal of Paramedic Practice. 2012b; 4:(12)688-9
Brady M Using patient experiences of emergency and unscheduled care for quality improvement. Journal of Paramedic Practice. 2012c; 4:(10)576-84
Brady M Challenges UK paramedics currently face in providing fully effective end-of-life care. Int J Palliat Nurs. 2014; 20:(1)37-44
Bradley PLondon: The Stationery Office; 2011
Breaden K, Phillips J, Agar M, Grbich C, Abernethy AP, Currow DC The clinical and social dimensions of prescribing palliative home oxygen for refractory dyspnea. J Palliat Med. 2013; 16:(3)268-73
Bruera E, Schoeller T, MacEachern T Symptomatic benefit of supplemental oxygen in hypoxemic patients with terminal cancer: the use of the N of 1 randomized controlled trial. J Pain Symptom Manage. 1992; 7:(6)365-8
Caraceni A, Brunelli C, Martini C, Zecca E, DeConno F Cancer pain assessment in clinical trials. A review of the literature. J Symptom Manage. 2005; 29:(5)507-19
Carr E Barriers to effective pain management. J Perioper Pract. 2007; 17:(5)200-208
Carr DB, Goudas LC, Balk EM, Bloch R, Ioannidis JP, Lau J Evidence report on the treatment of pain in cancer patients. J Natl Cancer Inst Mongor. 2004; (32)23-31
Chang V, Sorger B, Rosenfeld K Pain and palliative medicine. J Rehabil Res Dev. 2007; 44:(2)279-94
Chapman S Cancer pain part 2: assessment and management. Nurs Stand. 2012; 26:(48)44-9
Davis CL, Hodder C, Love S Effect of nebulised morphine and morphine-6-glucoronide on exercise endurance in patients with chronic obstructive pulmonary disease. Abstract of a presentation at the British Thoracic society's winter 1993 meeting. Thorax. 1994; 49
Dieckmann RA Rectal diazepam for prehospital pediatric status epilepticus. Ann Emerg Med. 1994; 23:(2)216-24
Dudgeon D In: Booth S, Dudgeon D (eds.). Oxford: Oxford University Press; 2006
Farncombe M Dyspnea: assessment and treatment. Support Care Cancer. 1997; 5:(2)94-9
Fitzgerald BJ, Okos AJ, Miller JW Treatment of out-of-hospital status epilepticus with diazepam rectal gel. Seizure. 2003; 12:(1)52-5
Glantz M, Recht LD(ed.). Amsterdam: Elsevior Publishing Company; 1997
Helfand M, Freeman M Assessment and management of acute pain in adult medical inpatients. Pain Med. 2009; 10:(7)1183-99
Hjermstad MJ, Gibbins J, Haugen DF Pain assessment tools in palliative care: an urgent need for consensus. Palliat Med. 2008; 22:(8)895-903
Hølen JC, Hjermstad MJ, Loge JH Pain assessment tools: is the content appropriate for use in palliative care. J Pain Symptom Manage. 2006; 32:(6)567-80
Jennings AL, Davies AN, Higgins JP, Broadley K Opioids for the palliation of breathlessness in advanced disease and terminal illness. Cochrane Database Syst Rev. 2012; (4)
Jennings AL, Davies AN, Higgins JP, Gibbs JS, Broadley KE A systematic review of the use of opioids in the management of dyspnoea. Thorax. 2002; 57:(11)939-44
, 66th edn.. London: BMJ Group and Pharmaceutical Press; 2013
Krouwer HG, Pallagi JL, Graves NM Management of seizures in brain tumor patients at the end of life. J Pallat Med. 2000; 3:(4)465-75
Lacasse Y, Goldstein R, Lasserson TJ, Martin S Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2006; (4)
LeGrand S Dyspnoea: the continuing challenge of palliative management. Curr Opin Oncol. 2002; 14:(4)394-8
Lord E Nebulized morphine: one intervention for endstage chronic obstructive pulmonary disorder. AARN News Lett. 1997; 53:(10)10-1
Lowenstein DH, Alldredge BK, Allen F The prehospital treatment of status epilepticus (PHTSE) study: design and methodology. Control Clin Trials. 2001; 22:(3)290-309
MacMillan SC, Weitzner MA Methodologic issues in collecting data from debilitated patients with cancer near the end-of-life. Oncol Nurs Forum. 2003; 30:(1)123-9
Macpherson CC Healthcare development requires stakeholder consultation: palliative care in the Caribbean. Camb Q Healthc Ethics. 2006; 15:(3)248-55
Macpherson C Undertreating pain violates ethical principles. J Med Ethics. 2009; 35:(10)603-6
Man GC, Hsu K, Sproule BJ Effect of alprazolam on exercise and dyspnea in patients with chronic obstructive pulmonary disease. Chest. 1986; 90:(6)832-6
McIver B, Walsh D, Nelson K The use of chlorpromazine for symptom control in dying cancer patients. J Pain Symptom Manage. 1994; 9:(5)341-5
Moots PL, Maciunas RJ, Eisert DR, Parker RA, Laporte K, Abou-Khalil B The course of seizure disorders in patients with malignant gliomas. Arch Neurol. 1995; 52:(7)717-24
Navigante AH, Cerchietti LC, Castro MA, Lutteral MA, Cabalar ME Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer. J Pain Symptom Manage. 2006; 31:(1)38-47
O'Driscoll M, Corner J, Bailey C The experience of breathlessness in lung cancer. Eur J Cancer Care. 1999; 8:(1)37-43
O'Neill PA, Morton PB, Stark RD Chlorpromazine—a specific effect on breathlessness?. Br J Clin Pharmacol. 1985; 19:(6)793-7
Pettifer A, Bronnert R End of life care in the community: the role of ambulance clinicians. Journal of Paramedic Practice. 2013; 5:(7)394-9
Rainbow J, Browne GJ, Lam LT Controlling seizures in the prehospital setting: diazepam or midazolam?. J Paediatr Child Health. 2002; 38:(6)582-6
Rice KL, Kronenberg RS, Hedemark LL, Niewoehner DE Effects of chronic administration of codeine and promethazine on breathlessness and exercise tolerance in patients with chronic airflow obstruction. Br J Dis Chest. 1987; 81:(3)287-92
Sampson FC, Goodacre SW Interventions to improve the management of pain in the emergency departments: Systematic review and narrative synthesis. Emerg Med J. 2014;
Saunders C, 1st edn.. New York: Oxford University Press; 2006
Schwartzstein RM, Manning HL, Weiss JW, Weinberger SE Dyspnea: a sensory experience. Lung. 1990; 168:(4)185-99
Scott RC, Besag FM, Neville BG Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: a randomised trial. Lancet. 1999; 353:(9153)623-6
Shearer F, Struthers A, Harbour R Opioids for treating dyspnoea with chronic heart failure. Cochrane Libr. 2014;
Sherwood P, Given BA, Given CW A cognitive behavioral intervention for symptom management in patients with advanced cancer. Oncol Nurs Forum. 2005; 32:(6)1190-8
Silbergleit R, Durkalski V, Lowenstein D Intramuscular versus intravenous therapy for prehospital status epilepticus. N Engl J Med. 2012; 366:(7)591-600
Simon ST, Higginson IJ, Booth S, Harding R, Bausewein C Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults. Cochrane Database Syst Rev. 2011; (1)
Steel K, Ljunggren G, Topinková E The RAI-PC: an assessment instrument for palliative care in all settings. Am J Hosp Palliat Care. 2003; 20:(3)211-19
Stone SC, Abbott J, McClung CD, Colwell CB, Echstein M, Lowenstein SR Paramedic knowledge, attitudes, and training in end-of-life care. Prehosp Disaster Med. 2009; 24:(6)529-34
Uronis HE, Currow DC, McCrory DC, Samsa GP, Abernethy AP Oxygen for relief of dyspnoea in mildly- or nonhypoxaemic patients with cancer. A systematic review and meta-analysis. Br J Cancer. 2008; 98:(2)294-9
Uronis H, McCrory DC, Samsa G, Currow D, Abernethy A Symptomatic oxygen for non-hypoxaemic chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2011; (6)
Westphal CG, Campbell ML Nebulized morphine for terminal dyspnea. Am J Nurs. 2002; 11-15
COPD management—a hospital physician's view. Respir Med COPD update. 2005; 1:3-17
Zeppetella G Nebulized morphine in the palliation of dyspnoea. Palliat Med. 1997; 11:(4)267-75