References

Aronson JK, Ferner RE. Drugs and the renin-angiotensin system in covid-19. BMJ. 2020; 369 https://doi.org/10.1136/bmj.m1313

Bai Y, Yao L, Wei T Presumed asymptomatic carrier transmission of COVID-19. JAMA. 2020; 323:(14)1406-1407 https://doi.org/10.1001/jama.2020.2565

Brady M, Jackson J, Northstone K. Remote clinical decision making: evaluation of a new education module. Nurse Educ Pract. 2018; 29:150-158 https://doi.org/10.1016/j.nepr.2018.01.002

British Cardiovascular Society. BSH & BCS joint statement on ACEi or ARB in relation to COVID-19. 2020. https//tinyurl.com/y8gm7ruf (accessed 19 April 2020)

Chan JF, Yuan S, Kok KH A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020; 395:(10223)514-523 https://doi.org/10.1016/s0140-6736(20)30154-9

Chen T, Wu D, Chen H Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ. 2020a; 368 https://doi.org/10.1136/bmj.m1091

Chen N, Zhou M, Dong X Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020b; 395:(10223)507-513 https://doi.org/10.1016/s0140-6736(20)30211-7

Consensus on Science with Treatment Recommendations. Brussels [Internet]: International Liaison Committee on Resuscitation (ILCOR); 30 March 2020. https//costr.ilcor.org/document/covid-19-infection-risk-to-rescuers-from-patients-in-cardiac-arrest (accessed 24 April 2020)

Department of Health and Social Care, Public Health England. Number of coronavirus (COVID-19) cases and risk in the UK. 2020. https//www.gov.uk/guidance/coronavirus-covid-19-information-for-the-public (accessed 18 April 2020)

Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?. Lancet Respir Med. 2020; 8:(4) https://doi.org/10.1016/s2213-2600(20)30116-8

Gamage B, Moore D, Copes R, Yassi A, Bryce E Protecting health care workers from SARS and other respiratory pathogens: a review of the infection control literature. Am J Infect Control. 2005; 33:(2)114-121 https://doi.org/10.1016/j.ajic.2004.12.002

Greenhalgh T, Koh GCH, Car J. Covid-19: a remote assessment in primary care. BMJ. 2020; 368 https://doi.org/10.1136/bmj.m1182

Greenberg N, Docherty M, Gnanapragasam S, Wessely S. Managing mental health challenges faced by healthcare workers during covid-19 pandemic. BMJ. 2020; 368 https://doi.org/10.1136/bmj.m1211

Guan WJ, Ni ZY, Hu Y Clinical characteristics of coronavirus Disease 2019 in China. N Engl J Med. 2020; https://doi.org/10.1056/NEJMoa2002032

Health Protection Scotland, NHS National Services Scotland. Aerosol generating procedures (AGPs). 2019. https//tinyurl.com/vptyovh (accessed 19 April 2020)

Huang C, Wang Y, Li X Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395:(10223)497-506 https://doi.org/10.1016/S0140-6736(20)30183-5

Trauma, recovery, and growth: positive psychological perspectives on posttraumatic stress. In: Joseph S, Linley PA (eds). Hoboken (NJ): John Wiley & Sons; 2008 https://doi.org/10.1002/9781118269718

Kucharski AJ, Russell TW, Diamond C Early dynamics of transmission and control of COVID-19: a mathematical modelling study. Lancet Infect Dis. 2020; https://doi.org/10.1016/s1473-3099(20)30144-4

Lake R, Georgiou A, Li J The quality, safety and governance of telephone triage and advice services—an overview of evidence from systematic reviews. BMC Health Serv Res. 2017; 17:(1) https://doi.org/10.1186/s12913-017-2564-x

Lauer SA, Grantz KH, Bi Q The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Intern Med. 2020; M20-0504 https://doi.org/10.7326/M20-0504

Li J, Leavey A, Yang W Defining aerosol generating procedures and pathogen transmission risks in healthcare settings. Open Forum Infect Dis. 2017; 4:S34-S35 https://doi.org/10.1093/ofid/ofx162.085

Li Q, Guan X, Wu P Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 2020; 382:(13)1199-1207 https://doi.org/10.1056/NEJMoa2001316

McCreary EK, Pogue JM. Coronavirus disease 2019 treatment: a review of early and emerging options. Open Forum Infect Dis. 2020; 7:(4) https://doi.org/10.1093/ofid/ofaa105

Medicines and Healthcare products Regulatory Agency and Commission on Human Medicines. Commission on Human Medicines advice on ibuprofen and coronavirus (COVID-19). 2020. https//tinyurl.com/y6uv32un (accessed 19 April 2020)

Mental Health Foundation. Looking after your mental health during the coronavirus outbreak. 2020. https//tinyurl.com/uju6mxj (accessed 18 April 2020)

Murray E. Moral injury and paramedic practice. J Paramedic Pract. 2019; 11:(10)424-425 https://doi.org/10.12968/jpar.2019.11.10.424

NHS. Think kidneys. 2020. https//www.thinkkidneys.nhs.uk/ (accessed 19 April 2020)

NHS England. More than one million people use NHS 111 online to get quick advice about coronavirus. 2020. https//tinyurl.com/y9jkvguw (accessed 19 April 2020)

NHS England and NHS Improvement. Important and urgent—next steps on NHS response to COVID-19. 2020. https//tinyurl.com/wjzllql (accessed 19 April 2020)

Public Health England. COVID-19: background information. 2020a. https//tinyurl.com/yx6qg94x (accessed 18 April 2020)

Public Health England. COVID-19: infection prevention and control (IPC). 2020b. https//tinyurl.com/rdp4ab4 (accessed 19 April)

Public Health England. COVID-19: guidance for ambulance trusts. 2020c. https//tinyurl.com/y78tz3gc (accessed 20 April 2020)

Public Health England. COVID-19: investigation and initial clinical management of possible cases. 2020d. https//tinyurl.com/v6xkw23 (accessed 19 April 2020)

Public Health England. COVID-19: guidance for households with possible coronavirus infection. 2020e. https//tinyurl.com/u25puoa (accessed 19 April 2020)

Qiao W, Wang C, Chen B Ibuprofen attenuates cardiac fibrosis in streptozotocin-induced diabetic rats. Cardiology. 2015; 131:(2)97-106 https://doi.org/10.1159/000375362

Razai MS, Doerholt K, Ladhani S, Oakeshott P. Coronavirus disease 2019 (covid-19): a guide for UK GPs. BMJ. 2020; 368 https://doi.org/10.1136/bmj.m800

Remuzzi A, Remuzzi G. COVID-19 and Italy: what next?. Lancet. 2020; 395:(10231)1225-1228 https://doi.org/10.1016/s0140-6736(20)30627-9

Renal Association. The Renal Association, UK position statement on COVID-19 and ACE inhibitor/angiotensin receptor blocker use. 2020. https//tinyurl.com/ya982avn (accessed 19 April 2020)

Resuscitation Council (UK). Statements on COVID-19 (coronavirus). 2020a. https//tinyurl.com/ww29mch (accessed 19 April 2020)

Resuscitation Council (UK). COVID-19: FAQs for healthcare professionals. 2020b. https//tinyurl.com/ycvxb2qb (accessed 17 April 2020)

Rothman KJ, Greenland S, Lash TL. Modern epidemiology.Philadelphia, PA: Lippincott-Raven; 2008

Royal College of General Practitioners. Top 10 tips For COVID-19 telephone consultations. 2020. https//tinyurl.com/ybcjfh9a (accessed19 April)

Royal Pharmaceutical Society. Advice on NSAIDs and COVID-19. 2020. https//tinyurl.com/yaj832qp (accessed 19 April 2020)

Russell B, Moss C, Rigg A, Van Hemelrijck M. COVID-19 and treatment with NSAIDs and corticosteroids: should we be limiting their use in the clinical setting?. Ecancermedicalscience. 2020; 14 https://doi.org/10.3332/ecancer.2020.1023

Tedeschi RG, Calhoun LG. Target article: posttraumatic growth: conceptual foundations and empirical evidence. Psychol Inq. 2004; 15:(1)1-18 https://doi.org/10.1207/s15327965pli1501_01

Tignanelli CJ, Ingraham NE, Sparks MA Antihypertensive drugs and risk of COVID-19?. Lancet Respir Med. 2020; https://doi.org/10.1016/s2213-2600(20)30153–3

Tran K, Cimon K, Severn M, Pessoa-Silva CL, Conly J. Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review. PLoS One. 2012; 7:(4) https://doi.org/10.1371/journal.pone.0035797

van Doremalen N, Bushmaker T, Morris DH Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med. 2020; 382:(16)1564-1567 https://doi.org/10.1056/NEJMc2004973

Wang W, Xu Y, Gao R Detection of SARS-CoV-2 in different types of clinical specimens. JAMA. 2020; https://doi.org/10.1001/jama.2020.3786

Wax RS, Christian MD. Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients. Can J Anaesth. 2020; 1-9 https://doi.org/10.1007/s12630-020-01591-x

Wheeler S, Mahlmeister L. Risk management in telephone triage part 1: new trends, advances & risks. 2016; https://doi.org/10.13140/rg.2.2.32472.70407

Williamson V, Greenberg N, Murphy D. Moral injury in UK armed forces veterans: a qualitative study. Eur J Psychotraumatol. 2019; 10:(1) https://doi.org/10.1080/20008198.2018.1562842

Williamson V, Stevelink SAM, Greenberg N. Occupational moral injury and mental health: systematic review and meta-analysis. Br J Psychiatry. 2018; 212:(6)339-346 https://doi.org/10.1192/bjp.2018.55

World Health Organization. Naming the coronavirus disease (COVID-19) and the virus that causes it. 2020a. https//tinyurl.com/t82w9ka (accessed 18 April 2020)

World Health Organization. Coronavirus disease 2019 (COVID-19). Situation report-78. 2020b. https//tinyurl.com/t82w9ka (accessed 18 April 2020)

World Health Organization. Rolling updates on coronavirus disease (COVID-19). Updated 23 March 2020. 2020c. https//www.who.int/docs/default-source/coronaviruse/mental-health-considerations.pdf (accessed 24 April 2020)

Xu X, Chen P, Wang J Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. Sci China Life Sci. 2020; 63:(3)457-460 https://doi.org/10.1007/s11427-020-1637-5

The new coronavirus disease: what do we know so far?

02 May 2020
Volume 12 · Issue 5

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that causes the new disease COVID-19. Symptoms range from mild to severe with a higher incidence of severe cases in patients with risk factors such as older age and comorbidities. COVID-19 is mainly spread through the inhalation of respiratory droplets from coughing or sneezing or via contact with droplet-contaminated surfaces. Paramedics should be aware that some aerosol-generating procedures may put them at a higher risk of contracting the virus via possible airborne transmission. Use of remote triage clinical assessment is likely to increase as a result of the pandemic. There is no curative drug treatment for the virus and some medications may exacerbate its effects or make patients more susceptible to it. Evidence and guidelines are evolving on SARS-CoV-2 and COVID-19. Paramedics should keep up to date with the latest clinical guidance from their employers.

In late December 2019, a novel coronavirus was identified in the Chinese city of Wuhan, causing severe respiratory disease including pneumonia (Public Health England (PHE), 2020a). In January 2020, the World Health Organization (WHO) named this novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated disease as COVID-19 (Chen et al, 2020a; PHE, 2020a; WHO, 2020a). The first confirmed case of COVID-19 in the UK was recorded on 31 January 2020 (Razai et al, 2019) and the number of cases has continued to rise since then (Figure 1).

Similar to other coronaviruses that have infected humans, SARS-CoV-2 are enveloped, positive-sense, single-stranded RNA viruses that cause respiratory infections (Chan et al, 2020; Xu et al, 2020). As with most human coronavirus infections, most SARS-CoV-2 infections induce mild respiratory disease and symptoms (Chen et al, 2020b; Huang et al, 2020).

Subscribe to get full access to the Journal of Paramedic Practice

Thank you for visiting the Journal of Paramedic Practice and reading our archive of expert clinical content. If you would like to read more from the only journal dedicated to those working in emergency care, you can start your subscription today for just £48.

What's included

  • CPD Focus

  • Develop your career

  • Stay informed